Rabbit polyclonal primary
Osteopontin Rabbit Polyclonal Antibody (0806-6)
Synthetic peptide within mouse osteopontin aa 245-294 / 294.
Mouse liver tissue lysates, rat kidney tissue lysate, mouse kidney tissue lysate, HepG2 cell lysate.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
BNSP antibody; Bone sialoprotein 1 antibody; BSP I antibody; BSPI antibody; Early T lymphocyte activation 1 antibody; ETA 1 antibody; ETA1 antibody; MGC110940 antibody; Nephropontin antibody; OPN antibody; Osteopontin antibody; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein antibody; OSTP_HUMAN antibody; PSEC0156 antibody; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) antibody; Secreted phosphoprotein 1 antibody; SPP 1 antibody; SPP-1 antibody; SPP1 antibody; SPP1/CALPHA1 fusion antibody; Urinary stone protein antibody; Uropontin antibody
Belongs to the osteopontin family.
Extensively phosphorylated by FAM20C in the extracellular medium at multiple sites within the S-x-E/pS motif.; O-glycosylated.
Osteopontin is an extracellular matrix cell adhesion protein which is abundant in bone and synthesized by preosteoblasts, osteoblasts and osteoclastic cells that are localized in the mineralized phase of bone matrix. Osteopontin probably exists in tissue-specific isoforms that may correspond to particular cellular functions. Acts as a cytokine it involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
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