Lane 1: Rat spleenl tissue lysate
Lane 2: Jurkat cell lysate
Lane 3: K562 cell lysate
Rabbit polyclonal primary
Nucleoside Phosphorylase Rabbit Polyclonal Antibody (HA500062)
Recombinant protein within human nucleoside phosphorylase aa 1-200.
Rat spleenl tissue lysate, Jurkat cell lysate, K562 cell lysate, human placenta tissue, human small intestine tissue.
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
Purine nucleoside phosphorylase PNP Inosine phosphorylase Inosine-guanosine phosphorylase
Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes inosine into hypoxanthine and guanosine into guanine, in each case creating ribose phosphate. Note: adenosine is first metabolized to inosine via the enzyme adenosine deaminase.One of the reaction catalyzed by purine nucleoside phosphorylase in purine metabolism.Nucleoside phosphorylase is an enzyme which cleaves a nucleoside by phosphorylating the ribose to produce a nucleobase and ribose 1 phosphate. It is one enzyme of the nucleotide salvage pathways. These pathways allow the cell to produce nucleotide monophosphates when the de novo synthesis pathway has been interrupted or is non-existent (as is the case in the brain). Often the de novo pathway is interrupted as a result of chemotherapy drugs such as methotrexate or aminopterin.All salvage pathway enzymes require a high energy phosphate donor such as ATP or PRPP.