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NSUN4 Rabbit Polyclonal Antibody (R1706-16)

Price: Regular price $315.00

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Catalog# R1706-16

Rabbit Polyclonal to NSUN4

Tested for

  • WB

  • IF-Cell

  • IHC-P

Reacts with

  • Human

  • Mouse

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

NSUN4 Rabbit Polyclonal Antibody (R1706-16)

Immunogen

Recombinant protein within n-terminal human nsun4.

Host

Rabbit

Positive Control

MCF-7, 293, A549, HepG2, human liver cancer tissue, human kidney tissue, mouse testis tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3073425

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IF-Cell

  • 1:50-1:200

  • IHC-P

  • 1:50-1:200

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 43 kDa

Isotype

IgG

TARGET

UNIPROT #

Q96CB9

PROTEIN NAME

NSUN4

SYNONYMS

5 methylcytosine rRNA methyltransferase NSUN4 antibody;EC=2.1.1.- antibody;NOL1/NOP2/Sun domain family member 4 antibody;NOL1/NOP2/Sun domain family, member 4 antibody;NOP2/Sun domain family, member 4 antibody;Nsun4 antibody;NSUN4_HUMAN antibody;Putative methyltransferase NSUN4 antibody;RP4-603I14.2 antibody;Shtap antibody;Sperm head and tail associated protein antibody

SEQUENCE SIMILARITIES

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

SUBCELLULAR LOCATION

Mitochondrion.

FUNCTION

Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.

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