Noggin Rabbit Polyclonal Antibody (0805-2)
Catalog# 0805-2
Rabbit Polyclonal to Noggin
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WB
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ICC
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IHC-P
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Human
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Mouse
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Rat
Specifications
Product Type
Rabbit polyclonal primary
Product Name
Noggin Rabbit Polyclonal Antibody (0805-2)
Immunogen
Synthetic peptide within n-terminal human noggin.
Host
Rabbit
Positive Control
MG-63, human brain, mouse brain
Conjugation
Unconjugated
Clonality
Polyclonal
APPLICATION DILUTION
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WB
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1:500-1:1,000
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ICC
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1:50-1:200
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IHC-P
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1:50-1:200
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
26kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
Noggin
SYNONYMS
Nog antibody;NOGG_HUMAN antibody;Noggin antibody;SYM 1 antibody;SYM1 antibody;Symphalangism 1 (proximal) antibody;Synostoses (multiple) syndrome 1 antibody;SYNS 1 antibody;SYNS1 antibody
SEQUENCE SIMILARITIES
Belongs to the noggin family.
SUBCELLULAR LOCATION
Secreted.
FUNCTION
Noggin is a bone morphogenetic protein (BMP) antagonist expressed in Spemann's organizer. Murine Noggin is expressed in condensing cartilage and immature chondrocytes, as are many BMPs. It is essential for cartilage morphogenesis and joint formation. Defects in NOG are the cause of multiple synostoses syndrome 1 (SYNS1), symphalangism proximal syndrome (SYM1) and tarsal-carpal coalition syndrome (TCC).
CITATIONS
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Zhao, Guiyun et al.
Cell surface proteomics analysis indicates a neural lineage bias of rat bone marrow mesenchymal stromal cells. | BioMed Research International [2014]
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WB
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IF
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rat
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Citation
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