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NMDAR2B Rabbit Polyclonal Antibody (HA500208)

Price: Regular price $315.00

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Catalog# HA500208

Rabbit Polyclonal to NMDAR2B

Tested for

  • WB

  • IF-Cell

  • IHC-P

  • FC

Reacts with

  • Mouse

  • Rat

  • Human

Specifications

Product Type

Rabbit polyclonal primary

Product Name

NMDAR2B Rabbit Polyclonal Antibody (HA500208)

Immunogen

Recombinant protein within human nmdar2b aa 1100-1300 / 1484.

Host

Rabbit

Positive Control

Mouse brain tissue lysate, rat brain tissue lysate, mouse hippocampus tissue lysate, A549, rat cerebellum tissue, MG-63.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071305

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IF-Cell

  • 1:50-1:100

  • IHC-P

  • 1:100-1:500

  • FC

  • 1:100-1:500

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

predicated 166 kDa

Isotype

IgG

TARGET

UNIPROT #

Q13224

PROTEIN NAME

NMDAR2B

SYNONYMS

AW490526 antibody;EIEE27 antibody;Glutamate [NMDA] receptor subunit epsilon 2 antibody;Glutamate [NMDA] receptor subunit epsilon-2 antibody;Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody;Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody;Glutamate receptor ionotropic NMDA2B antibody;Glutamate receptor subunit epsilon 2 antibody;Glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody;GRIN 2B antibody;GRIN2B antibody;hNR 3 antibody;hNR3 antibody;MGC142178 antibody;MGC142180 antibody;MRD6 antibody;N methyl D asparate receptor channel subunit epsilon 2 antibody;N methyl D aspartate receptor subtype 2B antibody;N methyl D aspartate receptor subunit 2B antibody;N methyl D aspartate receptor subunit 3 antibody;N-methyl D-aspartate receptor subtype 2B antibody;N-methyl-D-aspartate receptor subunit 3 antibody;NMDA NR2B antibody;NMDA R2B antibody;NMDAR2B antibody;NMDE2 antibody;NMDE2_HUMAN antibody;NME2 antibody;NR2B antibody;NR3 antibody;GluN2B

SUBCELLULAR LOCATION

Late endosome, cytoskeleton, cell membrane, postsynaptic cell membrane, lysosome.

FUNCTION

This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia.

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