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NMBR Rabbit Polyclonal Antibody (HA500253)

Price: Regular price $315.00

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Catalog# HA500253

Rabbit Polyclonal to NMBR

Tested for

  • WB

  • IHC-P

Reacts with

  • Human

  • Mouse

  • Rat

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COA DOWNLOAD

Specifications

Product Type

Rabbit polyclonal primary

Product Name

NMBR Rabbit Polyclonal Antibody (HA500253)

Immunogen

Synthetic peptide within human nmbr aa 1-41 (extracellular domain).

Host

Rabbit

Positive Control

A549 cell lysate, rat brain tissue lysate, mouse testis tissue lysate, rat testis tissue, human fallopian tube tissue, mouse brain tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071349

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IHC-P

  • 1:100-1:500

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

43 kDa

Isotype

IgG

TARGET

UNIPROT #

P28336

PROTEIN NAME

NMBR

SYNONYMS

Neuromedin B preferring bombesin receptor antibody;Neuromedin B receptor antibody;Neuromedin-B receptor antibody;Neuromedin-B-preferring bombesin receptor antibody;NMB R antibody;NMB-R antibody;Nmbr antibody;NMBR_HUMAN antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants.

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