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NDE1 Rabbit Polyclonal Antibody (HA500198)

Price: Regular price $315.00

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Catalog# HA500198

Rabbit Polyclonal to NDE1

Tested for

  • WB

  • IHC-P

  • FC

Reacts with

  • Human

  • Rat

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

NDE1 Rabbit Polyclonal Antibody (HA500198)

Immunogen

Recombinant protein within human nde1 aa 1-200.

Host

Rabbit

Positive Control

Rat brain tissue lysates, rat cerebellum tissue, human liver tissue, Hela.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071295

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:100-1:500

  • FC

  • 1:500-1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

38 kDa

Isotype

IgG

TARGET

UNIPROT #

Q9NXR1

PROTEIN NAME

NDE1

SYNONYMS

FLJ20101 antibody;HOM TES 87 antibody;LIS1 interacting protein NUDE1 rat homolog antibody;LIS1 interacting protein NUDE1 antibody;LIS4 antibody;NDE 1 antibody;NDE1 antibody;NDE1_HUMAN antibody;Nuclear distribution gene E homolog 1 antibody;Nuclear distribution protein nudE homolog 1 antibody;NUDE 1 antibody;NudE antibody;NudE nuclear distribution gene E homolog 1 (A. nidulans) antibody;NudE nuclear distribution gene E homolog 1 antibody;NUDE1 antibody

SUBCELLULAR LOCATION

Cytoskeleton, centrosome, spindle, kinetochore, cleavage furrow.

FUNCTION

This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants.

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