MST4 Recombinant Rabbit Monoclonal Antibody [JE64-64] (HA721094)

UNIPROT #

Q9P289

PROTEIN NAME

MST4

SYNONYMS

2610018G03Rik antibody;EC 2.7.11.1 antibody;Mammalian Ste20 like protein kinase 4 antibody;Mammalian STE20-like protein kinase 4 antibody;Mammalian sterile 20 like 4 antibody;MASK antibody;MST 4 antibody;MST-4 antibody;MST3 and SOK1 related kinase antibody;Mst3 and SOK1-related kinase antibody;Mst4 antibody;MST4_HUMAN antibody;RGD1563568 antibody;RP23-245F8.1 antibody;RP6 213H19.1 antibody;Serine/threonine protein kinase 26 antibody;Serine/threonine protein kinase MASK antibody;Serine/threonine protein kinase MST 4 antibody;Serine/threonine protein kinase MST4 antibody;Serine/threonine-protein kinase MASK antibody;Serine/threonine-protein kinase MST4 antibody;STE20 like kinase MST 4 antibody;STE20 like kinase MST4 antibody;STE20-like kinase MST4 antibody;STK26 antibody

SUBCELLULAR LOCATION

Golgi apparatus, Cytoplasm.

FUNCTION

Serine/threonine protein kinase MST4, also known as mammalian STE20-like protein kinase 4 (MST-4), is a protein that in humans is encoded by the MST4 gene. The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.