Rabbit polyclonal primary
MSI2 Rabbit Polyclonal Antibody (ER1706-59)
Recombinant protein within human msi2 aa 1-185 / 328.
SW480, K562, HepG2, PC-12, SH-SY5Y, rat epididymis tissue, human breast tissue, human placenta tissue, mouse brain tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
FLJ36569 antibody; MGC3245 antibody; Msi2 antibody; MSI2/HOXA9 fusion gene, included antibody; MSI2H antibody; MSI2H_HUMAN antibody; Musashi 2 antibody; Musashi homolog 2 antibody; Musashi RNA binding protein 2 antibody; Musashi, Drosophila, homolog of, 2 antibody; Musashi-2 antibody; RNA binding protein Musashi homolog 2 antibody; RNA-binding protein Musashi homolog 2 antibody; WD 40 repeat protein MSI2 antibody
Belongs to the Musashi family.
Ubiquitous; detected at low levels.
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to post-translational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.