MRPL28 Recombinant Rabbit Monoclonal Antibody [JE55-90] (ET7111-30)

UNIPROT #

Q13084

PROTEIN NAME

MRPL28

SYNONYMS

39S ribosomal protein L28 antibody;39S ribosomal protein L28 mitochondrial antibody;39S ribosomal protein L28 mitochondrial precursor antibody;HGNC6756 antibody;L28mt antibody;MAAT 1 antibody;MAAT1 antibody;Melanoma antigen p15 antibody;Melanoma associated antigen recognised by cytotoxic T lymphocytes antibody;Melanoma associated antigen recognized by T lymphocytes antibody;Melanoma-associated antigen recognized by T-lymphocytes antibody;MGC8499 antibody;mitochondrial antibody;Mitochondrial ribosomal protein L28 antibody;MRP L28 antibody;MRP-L28 antibody;MRPL 28 antibody;mrpl28 antibody;P15 antibody;RM28_HUMAN antibody

SUBCELLULAR LOCATION

Mitochondrion.

FUNCTION

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion.