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Mouse CD48/SLAMF2, C-His Tag Protein (HA211237)

Price: Regular price $129.00

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Catalog# HA211237

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  • Mouse

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Product Details

Product Type

Protein

Product Name

Mouse CD48/SLAMF2, C-His Tag Protein (HA211237)

Predicted molecular mass

24.2 kD

Protein construction description

A DNA sequence encoding the mouse CD48/SLAMF2 (P18181) (Phe 23-Ser 217) was expressed with a His tag at the C-terminus.

Accession

P18181

Protein construction

CD48/SLAMF2 (23-217) | His

Source

HEK293

Bio Activity

Testing in progress.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Mouse

Background

CD48 is a glycosylphosphatidylinositol (GPI) -anchored membrane protein of the signaling lymphocyte activation molecule (SLAM) family, also known as SLAMF2 and BLAST-1. It is constitutively expressed on most hematopoietic cells (not on neutrophils and a subset of long-term hematopoietic stem cells in mice) and can be upregulated under certain conditions like infection. Interaction with its low affinity ligand CD2 promotes adhesion and TCR signaling. Interaction with the high affinity ligand CD244 (2B4) regulates natural killer (NK) and CD8 T cell activation and cytolytic function.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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