PRODUCT CODE: R1408-8

Monoamine oxidase A Rabbit Polyclonal Antibody (R1408-8)

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

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Western blot analysis on cell and tissue lysates using anti- MAOA rabbit polyclonal antibodies.
  • Western blot analysis on cell and tissue lysates using anti- MAOA rabbit polyclonal antibodies.
Western blot analysis on cell and tissue lysates using anti- MAOA rabbit polyclonal antibodies.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

Monoamine oxidase A Rabbit Polyclonal Antibody (R1408-8)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Human liver, HepG2, rat brain

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Peptide affinity purified

MOLECULAR WEIGHT

60 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:1000-1:2,000

TARGET

UNIPROT #

PROTEIN NAME

Monoamine oxidase A

SYNONYMS

Amine oxidase [flavin containing] A antibody; Amine oxidase [flavin-containing] A antibody; AOFA antibody; AOFA_HUMAN antibody; EC 1.4.3.4 antibody; MAO A antibody; MAO-A antibody; maoA antibody; Monoamine oxidase A antibody; Monoamine oxidase type A antibody

SEQUENCE SIMILARITIES

Belongs to the flavin monoamine oxidase family.

TISSUE SPECIFICITY

Heart, liver, duodenum, blood vessels and kidney.

SUBCELLULAR LOCATION

Mitochondrion outer membrane

FUNCTION

Monoamine oxidase A is an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the outer mitochondrial membrane. Its encoding gene is adjacent to a related gene (MAOB) on the opposite strand of the X chromosome. MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34% in patients with major depressive disorder. Genetic association studies examining the relationship between high-activity MAOA variants and depression have produced mixed results, with some studies linking the high-activity variants to major depression in females, depressed suicide in males, major depression and sleep disturbance in males and major depressive disorder in both males and females.