Rabbit polyclonal primary
Monoamine oxidase A Rabbit Polyclonal Antibody (R1408-8)
Human liver, HepG2, rat brain
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified
Monoamine oxidase A
Amine oxidase [flavin containing] A antibody; Amine oxidase [flavin-containing] A antibody; AOFA antibody; AOFA_HUMAN antibody; EC 18.104.22.168 antibody; MAO A antibody; MAO-A antibody; maoA antibody; Monoamine oxidase A antibody; Monoamine oxidase type A antibody
Belongs to the flavin monoamine oxidase family.
Heart, liver, duodenum, blood vessels and kidney.
Mitochondrion outer membrane
Monoamine oxidase A is an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the outer mitochondrial membrane. Its encoding gene is adjacent to a related gene (MAOB) on the opposite strand of the X chromosome. MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34% in patients with major depressive disorder. Genetic association studies examining the relationship between high-activity MAOA variants and depression have produced mixed results, with some studies linking the high-activity variants to major depression in females, depressed suicide in males, major depression and sleep disturbance in males and major depressive disorder in both males and females.