MNK2 Rabbit Polyclonal Antibody (HA500543)

UNIPROT #

Q9HBH9

PROTEIN NAME

MNK2

SYNONYMS

G protein coupled receptor kinase 7 antibody;GPRK7 antibody;MAP kinase interacting serine threonine kinase 2 antibody;MAP kinase interacting serine threonine kinase antibody;MAP kinase interacting serine threonine protein kinase 2 antibody;MAP kinase signal integrating kinase 2 antibody;MAP kinase signal-integrating kinase 2 antibody;MAP kinase-interacting serine/threonine-protein kinase 2 antibody;MAPK interacting kinase 2 antibody;MAPK signal integrating kinase 2 antibody;Mitogen activated protein kinase interacting serine threonine kinase 2 antibody;Mknk2 antibody;MKNK2_HUMAN antibody;Mnk2 antibody;Putative map kinase interacting kinase antibody

SUBCELLULAR LOCATION

Nucleus, PML body; Cytoplasm.

FUNCTION

MAP kinase-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MKNK2 gene. MNK2 has been shown to interact with MAPK1 and Eukaryotic translation initiation factor 4 gamma. MNK2 has been identified as a therapeutic target for diabetes. Specifically, blocking MNK2 interaction with eIF4G has been shown to boost protein synthesis and promote beta cell regeneration.