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Mitoferrin1 Rabbit Polyclonal Antibody (HA500278)

Price: Regular price $315.00

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Catalog# HA500278

Rabbit Polyclonal to Mitoferrin1

Tested for

  • WB

  • IF-Cell

  • IHC-P

Reacts with

  • Human

  • Mouse

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

Mitoferrin1 Rabbit Polyclonal Antibody (HA500278)

Immunogen

Synthetic peptide within human mitoferrin1 aa 289-338.

Host

Rabbit

Positive Control

Mouse spleen tissue lysates, mouse brain tissue lysate, THP-1 cell lysate, Hela, mouse brain tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3073482

APPLICATION DILUTION

  • WB

  • 1:500

  • IF-Cell

  • 1:50

  • IHC-P

  • 1:400

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 37 kDa

Isotype

IgG

TARGET

UNIPROT #

Q9NYZ2

PROTEIN NAME

Mitoferrin1

SYNONYMS

HT015 antibody;MFRN antibody;Mitochondrial iron transporter 1 antibody;Mitochondrial solute carrier protein antibody;Mitoferrin 1 antibody;MSC antibody;MSCP antibody;predicted protein of HQ2217 antibody;PRO1278 antibody;PRO1584 antibody;PRO2217 antibody;Solute carrier family 25 member 37 antibody;SLC25A37

SUBCELLULAR LOCATION

Mitochondrion inner membrane.

FUNCTION

SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009). Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By similarity).

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