Lane 1: SiHa cell lysate
Lane 2: HepG2 cell lysate
Lane 3: A549 cell lysate
Lane 4: U937 cell lysate
Mouse monoclonal primary
MGST1 Mouse Monoclonal Antibody [14H2] (EM1901-13)
Recombinant protein within human mgst1 aa 1-144 / 155.
SiHa cell lysate, HepG2 cell lysate, A549 cell lysate, U937 cell lysate, zebrafish tissue lysates, rat kidney tissue, human liver carcinoma tissue, human colon tissue, human placenta tissue, mouse liver tissue, MCF-7.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
MGST1 antibody; Glutathione S transferase 12 antibody; GST12 antibody; MGST 1 antibody; MGST antibody; MGST I antibody; MGST1 antibody; MGST1_HUMAN antibody; Microsomal glutathione S-transferase 1 antibody; Microsomal GST 1 antibody; Microsomal GST-1 antibody; Microsomal GST-I antibody
Belongs to the MAPEG family.
Highly expressed in liver.
Peroxynitrite induces nitration at Tyr-93 which activates the enzyme.
Endoplasmic reticulum, Mitochondrion.
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene.