Positive control:
Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Applications
-
WB
-
IHC-P
-
FC
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
MFF Rabbit Polyclonal Antibody (ER1902-93)
Immunogen
Synthetic peptide within human mff aa 160-200.
Host
Rabbit
Positive Control
Hela cell lysate, HepG2 cell lysate, rat testis tissue, mouse testis tissue, K562.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 1% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
PURIFICATION
Immunogen affinity purified.
MOLECULAR WEIGHT
38 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500
-
IHC-P
-
1:50-1:100
-
FC
-
1:50-1:100
TARGET
UNIPROT #
PROTEIN NAME
MFF
SYNONYMS
C2orf33 antibody;Chromosome 2 open reading frame 33 antibody;DKFZp666J168 antibody;GL004 antibody;Mff antibody;MFF_HUMAN antibody;MGC110913 antibody;Mitochondrial fission factor antibody;OTTHUMP00000164235 antibody
SUBCELLULAR LOCATION
Mitochondrion outer membrane, Peroxisome, synaptic vesicle.
FUNCTION
This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants. Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.