MFF Rabbit Polyclonal Antibody (ER1902-93)

UNIPROT #

Q9GZY8

PROTEIN NAME

MFF

SYNONYMS

C2orf33 antibody;Chromosome 2 open reading frame 33 antibody;DKFZp666J168 antibody;GL004 antibody;Mff antibody;MFF_HUMAN antibody;MGC110913 antibody;Mitochondrial fission factor antibody;OTTHUMP00000164235 antibody

SUBCELLULAR LOCATION

Mitochondrion outer membrane, Peroxisome, synaptic vesicle.

FUNCTION

This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants. Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.