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MEMO1 Rabbit Polyclonal Antibody (HA500024)

Price: Regular price $315.00

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Catalog# HA500024

Rabbit Polyclonal to MEMO1

Tested for

  • WB

  • IHC-P

Reacts with

  • Human

  • Mouse

  • Rat

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

MEMO1 Rabbit Polyclonal Antibody (HA500024)

Immunogen

Recombinant protein within human memo1 aa 1-200.

Host

Rabbit

Positive Control

Mouse lung tissue lysate, Mouse colon tissue lysate, human colon tissue, mouse colon tissue, rat colon tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071124

APPLICATION DILUTION

  • WB

  • 1:1,000-1:2,000

  • IHC-P

  • 1:5,000

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 34 kDa.

Isotype

IgG

TARGET

UNIPROT #

Q9Y316

PROTEIN NAME

MEMO1

SYNONYMS

C21orf19-like protein antibody;C2orf4 antibody;CGI 27 antibody;DKFZp434I0135 antibody;FLJ25031 antibody;HCV NS5A-transactivated protein 7 antibody;Hepatitis C virus NS5A-transactivated protein 7 antibody;Mediator of cell motility 1 antibody;Mediator of ErbB2-driven cell motility 1 antibody;MEMO antibody;Memo-1 antibody;memo1 antibody;MEMO1_HUMAN antibody;NS5ATP7 antibody;Protein MEMO1 antibody

SUBCELLULAR LOCATION

Cytosol, nucleus.

FUNCTION

May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.

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