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Meckelin Rabbit Polyclonal Antibody (0903-7)

Price: Regular price $315.00

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Catalog# 0903-7

Rabbit Polyclonal to Meckelin

Tested for

  • WB

  • IHC-P

  • FC

Reacts with

  • Human

  • Mouse

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

Meckelin Rabbit Polyclonal Antibody (0903-7)

Immunogen

Synthetic peptide within human meckelin aa 20-80.

Host

Rabbit

Positive Control

MCF-7 cell lysates, mouse kidney tissue, human placenta tissue, human breast cancer tissue, PANC-1.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3068704

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:50-1:200

  • FC

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

112 kDa

Isotype

IgG

TARGET

UNIPROT #

Q5HYA8

PROTEIN NAME

Meckelin

SYNONYMS

JBTS6 antibody;Meckel syndrome type 3 protein antibody;MKS3 antibody;NPHP11 antibody;TMEM67 antibody;TNEM67 antibody;Transmembrane protein 67 antibody

SUBCELLULAR LOCATION

Cytoskeleton, Plasma membrane, Endoplasmic reticulum.

FUNCTION

Required for ciliary structure and function. Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Involved in centrosome migration to the apical cell surface during early ciliogenesis. Involved in the regulation of cilia length and appropriate number through the control of centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (SFTPC).

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