MAOA Mouse Monoclonal Antibody [5D1] (EM1701-54)

UNIPROT #

P21397

PROTEIN NAME

MAOA

SYNONYMS

Amine oxidase [flavin containing] A antibody;Amine oxidase [flavin-containing] A antibody;AOFA antibody;AOFA_HUMAN antibody;EC 1.4.3.4 antibody;MAO A antibody;MAO-A antibody;maoA antibody;Monoamine oxidase A antibody;Monoamine oxidase type A antibody

SEQUENCE SIMILARITIES

Belongs to the flavin monoamine oxidase family.

TISSUE SPECIFICITY

Heart, liver, duodenum, blood vessels and kidney.

SUBCELLULAR LOCATION

Mitochondrion outer membrane.

FUNCTION

This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. Has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues.This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.