Lane 1: Jurkat
Lane 2: 293T
Lane 3: Human skin
Recombinant Rabbit monoclonal primary
Lumican Recombinant Rabbit Monoclonal Antibody [JE11-45] (ET7109-24)
Recombinant protein within human lumican aa 50-250.
Jurkat, 293T, Human skin tissue, MCF-7, MG-63, PANC-1, rat kidney tissue, human skin tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Keratan sulfate proteoglycan lumican antibody; KSPG lumican antibody; LDC antibody; LUM antibody; LUM_HUMAN antibody; Lumican antibody; Lumican precursor antibody; SLRR2D antibody
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
Cornea and other tissues.
Present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan.
Sulfated on tyrosine residue(s).
Extracellular matrix. Secreted.
Lumican, a member of the small leucine-rich proteoglycans (SLRPs) family of proteins, is a keratan sulfate proteoglycan present in large quantities in the corneal stroma and in interstitial collagenous matrices of the heart, aorta, skeletal muscle, skin, and intervertebral discs. During collagen fibrillogenesis, lumican regulates the assembly of collagens into higher order fibrils, limiting the growth of fibrils in diameter. Lumican is present in the extracellular matrix of human articular cartilage at all ages, with a far greater abundance in the adult. The gene encoding human lumican maps to chromosome 12q21.3-q22.