LSS Rabbit Polyclonal Antibody (HA500011)
Catalog# HA500011
Rabbit Polyclonal to LSS
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WB
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IHC-P
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Human
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Mouse
Positive control:
Lane 1: HepG2 cell lysate
Lane 2: K562 cell lysate
Lane 3: Human liver tissue lysate
Specifications
Product Type
Rabbit polyclonal primary
Product Name
LSS Rabbit Polyclonal Antibody (HA500011)
Immunogen
Recombinant protein within human lss aa 1-200.
Host
Rabbit
Positive Control
HepG2 cell lysate, K562 cell lysate, human liver tissue lysate, human colon carcinoma tissue, human skin tissue, human placenta tissue, mouse liver tissue.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:500-1:1,000
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IHC-P
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1:100-1:500
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 74 kDa.
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
LSS
SYNONYMS
2,3 epoxysqualene lanosterol cyclase antibody;LSS;hOSC antibody;Lanosterol synthase (2,3 oxidosqualene lanosterol cyclase) antibody;Lanosterol synthase antibody;OSC antibody;Oxidosqualene lanosterol cyclase antibody
SUBCELLULAR LOCATION
Endoplasmic reticulum membrane.
FUNCTION
The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.
CITATIONS
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Yue Liu , Huasong Zhang , Cong Fan , Feiyi Liu , Shaoying Li , Juanjuan Li , Huiying Zhao , Xianhai Zeng
Potential role of Bcl2 in lipid metabolism and synaptic dysfunction of age-related hearing loss
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WB
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Rat
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Citation
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