Applications
-
WB
-
IHC-P
-
IP
REACTIVITY
-
Human
SPECIFICATIONS
Product Type
Recombinant Rabbit monoclonal primary
Product Name
LRG1 Recombinant Rabbit Monoclonal Antibody [JB34-31] (ET7107-11)
Immunogen
Recombinant protein
Host
Rabbit
Positive Control
Human serum, human kidney tissue.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
JB34-31
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein A purified.
MOLECULAR WEIGHT
38 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500-1:2,000
-
IHC-P
-
1:50-1:200
-
IP
-
1:10-1:50
TARGET
UNIPROT #
PROTEIN NAME
LRG1
SYNONYMS
1300008B03Rik antibody; 2310031E04Rik antibody; A2GL antibody; A2GL_HUMAN antibody; HMFT1766 antibody; Leucine rich alpha 2 glycoprotein antibody; Leucine-rich alpha-2-glycoprotein 1 antibody; Leucine-rich alpha-2-glycoprotein antibody; Leucine-rich alpha-2-glycoprotein precursor antibody; LRG antibody; LRG1 antibody
TISSUE SPECIFICITY
Plasma.
SUBCELLULAR LOCATION
Secreted.
FUNCTION
LRG1 (leucine-rich alpha-2-glycoprotein), also known as LRG, is a 347 amino acid secreted protein that contains eight LRR (leucine-rich repeats) and one LRRCT domain. The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Found mainly in plasma, LRG1 is expressed during granulocyte differentiation. The gene that encodes LRG1 consists of nearly 3,000 bases and maps to human chromosome 19p13.3. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).