LPA receptor 1 Rabbit Polyclonal Antibody (0902-5)
Catalog# 0902-5
Rabbit Polyclonal to LPA receptor 1
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WB
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IHC-P
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Mouse
Specifications
Product Type
Rabbit polyclonal primary
Product Name
LPA receptor 1 Rabbit Polyclonal Antibody (0902-5)
Immunogen
Synthetic peptide within n-terminal mouse lpa receptor 1.
Host
Rabbit
Positive Control
Mouse liver
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:1,000
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 41 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
LPA receptor 1
SYNONYMS
5031439C20 antibody;AI326300 antibody;EDG 2 antibody;Endothelial differentiation gene 2 antibody;Endothelial differentiation, lysophosphatidic acid G protein coupled receptor, 2 antibody;GPCR 26 antibody;Gpcr26 antibody;Gpcr91 antibody;GPR26 antibody;Kdt2 antibody;LPA 1 antibody;LPA receptor 1 antibody;LPA receptor EDG2 antibody;LPA-1 antibody;lpA1 antibody;Lpar1 antibody;LPAR1_HUMAN antibody;Lysophosphatidic acid receptor 1 antibody;Lysophosphatidic acid receptor Edg-2 antibody;Lysophosphatidic acid receptor EDG2 antibody;MGC105279 antibody;MGC29102 antibody;Mrec1.3 antibody;rec.1.3 antibody;Ventricular zone gene 1 antibody;vzg-1 antibody;VZG1 antibody
SEQUENCE SIMILARITIES
Belongs to the G-protein coupled receptor 1 family.
TISSUE SPECIFICITY
Detected in brain corpus callosum, medulla oblongata, cerebellum and sciatic nerve. Detected in heart.
POST-TRANSLATIONAL MODIFICATION
N-glycosylated.
SUBCELLULAR LOCATION
Cell surface, Cell membrane, Endosome.
FUNCTION
Lysophosphatidic acid receptor 1 also known as LPAR1 is a gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule lysophosphatidic acid (LPA). The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Alternative splicing of this gene has been observed and two transcript variants have been described, each encoding identical proteins.
CITATIONS
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Ming Zhang
Cell Surface Proteomics Analysis Indicates a Neural Lineage Bias of Rat Bone Marrow Mesenchymal Stromal Cells
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WB
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IF
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rat
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Citation
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