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LINE-1 ORF1p Rabbit Polyclonal Antibody (R1411-1)

Price: Regular price $315.00

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Catalog# R1411-1

Rabbit Polyclonal to L1ORF1p

Tested for

  • WB

  • IF-Cell

Reacts with

  • Mouse

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

LINE-1 ORF1p Rabbit Polyclonal Antibody (R1411-1)

Immunogen

Synthetic peptide within mouse line-1 orf1p aa 308-357 / 357.

Host

Rabbit

Positive Control

Mouse testis tissue lyaste, Mouse ovary tissue lyaste.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3073306

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IF-Cell

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 41 kDa

Isotype

IgG

TARGET

UNIPROT #

P11260

PROTEIN NAME

L1ORF1p

SYNONYMS

L12R1_HUMAN antibody;loh12cr1 antibody;Loss of heterozygosity 12 chromosomal region 1 protein antibody

SEQUENCE SIMILARITIES

Belongs to the transposase 22 family.

TISSUE SPECIFICITY

Expressed in meiotic spermatocytes and in the cerebellum (at protein level).

POST-TRANSLATIONAL MODIFICATION

Polyubiquitinated, probably by UBR2, which induces its degradation.

SUBCELLULAR LOCATION

Cytoplasm, nucleus.

FUNCTION

The L1 (LINE 1) retrotransposable element encodes two proteins, ORF1p and ORF2p. Mouse ORF1p, a coiled-coil-mediated trimer of 42-kDa monomers. It may function as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.

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