Lane 1: Hela cell lysate
Lane 2: Human brain tissue lysate
Recombinant Rabbit monoclonal primary
L1CAM Recombinant Rabbit Monoclonal Antibody [JM11-05] (ET1703-51)
Recombinant protein within human l1cam aa 900-1120.
Hela, human brain, human kidney tissue, human thyroid tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Antigen identified by monoclonal antibody; R1 antibody; CAML1 antibody; CD171 antibody; CD171 antigen antibody; HSAS antibody; HSAS1 antibody; Hyd antibody; L1 antibody; L1 cell adhesion molecule antibody; L1-NCAM antibody; L1cam antibody; L1CAM_HUMAN antibody; MASA antibody; MIC5 antibody; N CAML1 antibody; N-CAM-L1 antibody; NCAM-L1 antibody; NCAML1 antibody; Nerve-growth factor-inducible large external glycoprotein antibody; Neural cell adhesion molecule L1 antibody; NILE antibody; OTTHUMP00000025992 antibody; S10 antibody; SPG1 antibody
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors, including neuroblastomas, rhabdomyosarcomas, Wilm's tumors, Ewing's sarcomas and some primitive myeloid malignancies. The NCAM-L1 adhesion molecule (CD171) plays an important role in axon guidance and cell migration in the nervous system. The presence of NCAM-L1 might contribute to tumor progression by promoting cell adhesion and migration and is known to be expressed by neurons, neuroblastomas and other malignant tumors.