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KV4.3 Rabbit Polyclonal Antibody (ER1802-91)

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Catalog# ER1802-91

Rabbit Polyclonal to KV4.3

Tested for

  • WB

  • ICC

  • IHC-P

  • FC

React with

  • Human

  • Mouse

Specifications

Product Type

Rabbit polyclonal primary

Product Name

KV4.3 Rabbit Polyclonal Antibody (ER1802-91)

Immunogen

Synthetic peptide within human kv43 aa 435-484 / 655.

Host

Rabbit

Positive Control

MCF-7, mouse marrow tissue, LOVO, MG-63, human esophagus tissue, human placenta tissue, mouse cerebellum tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • ICC

  • 1:200

  • IHC-P

  • 1:50-1:200

  • FC

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

73 kDa

Isotype

IgG

TARGET

UNIPROT #

Q9UK17

PROTEIN NAME

KV4.3

SYNONYMS

KCND 3 antibody;KCND 3L antibody;KCND 3S antibody;Kcnd3 antibody;KCND3_HUMAN antibody;KCND3L antibody;KCND3S antibody;KSHIVB antibody;Kv 4.3 antibody;MGC14203 antibody;MGC142037 antibody;OTTHUMP00000063948 antibody;Potassium ioinic channel Kv4.3 antibody;Potassium voltage gated channel Shal related subfamily member 3 antibody;Potassium voltage gated channel subfamily D member 3 antibody;Potassium voltage-gated channel subfamily D member 3 antibody;Sha1 related potassium channel Kv4.3 antibody;Voltage gated K+ channel antibody;Voltage gated potassium channel Kv4.3 antibody;Voltage gated potassium channel subunit Kv4.3 antibody;Voltage-gated potassium channel subunit Kv4.3 antibody

SEQUENCE SIMILARITIES

Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.3/KCND3 sub-subfamily.

TISSUE SPECIFICITY

Highly expressed in heart and brain, in particular in cortex, cerebellum, amygdala and caudate nucleus. Detected at lower levels in liver, skeletal muscle, kidney and pancreas. Isoform 1 predominates in most tissues. Isoform 1 and isoform 2 are detected at similar levels in brain, skeletal muscle and pancreas.

POST-TRANSLATIONAL MODIFICATION

Regulated through phosphorylation at Ser-569 by CaMK2D.

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.

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