KCNK4 / K2P4.1 Rabbit Polyclonal Antibody (ER1803-07)

UNIPROT #

Q9NYG8

PROTEIN NAME

K2P4.1

SYNONYMS

K2p4.1 antibody;K2P4.1 potassium channel antibody;KCNK 4 antibody;MGC144821 antibody;Potassium channel subfamily K member 4 antibody;Potassium inwardly rectifying channel subfamily K member 4 antibody;TRAAK antibody;TRAAK1 antibody;TRAAKt antibody;TWIK related arachidonic acid stimulated potassium channel protein antibody;Two pore K(+) channel KT4.1 antibody;Two pore K+ channel KT4.1 antibody;Two pore potassium channel KT4.1 antibody

SEQUENCE SIMILARITIES

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

POST-TRANSLATIONAL MODIFICATION

N-glycosylated.

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

K2P4.1 (also named TWIK-related arachidonic acid stimulated K+ channel, TRAAK or KCNK4) is a member of the 2-pore (2P) domain K+ channels family that at the moment includes 15 members. These channels show little time or voltage dependence and are considered to be “leaky” or “background” K+ channels, thereby generating background currents which help set the membrane resting potential and cell excitation. The K2P channels have a signature topology that includes four transmembrane domains and two pore domains with intracellular N- and C- termini.