PRODUCT CODE: M1305-3

Interleukin 31 Mouse Monoclonal Antibody [B7-B0] (M1305-3)

Applications

  • WB

  • ELISA

REACTIVITY

  • Human

Western blot analysis on bioactive recombinant human IL-31 protein using anti-IL-31 Mouse mAb (Cat. # M1305-3).
  • Western blot analysis on bioactive recombinant human IL-31 protein using anti-IL-31 Mouse mAb (Cat. # M1305-3).
Western blot analysis on bioactive recombinant human IL-31 protein using anti-IL-31 Mouse mAb (Cat. # M1305-3).

Applications

  • WB

  • ELISA

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Mouse monoclonal primary

Product Name

Interleukin 31 Mouse Monoclonal Antibody [B7-B0] (M1305-3)

Immunogen

Recombinant protein

Host

Mouse

Positive Control

Bioactive recombinant human IL-31 protein

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

B7-B0

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

18kDa

Isotype

IgG2a

APPLICATION DILUTION

  • WB

  • 1:2,000

  • ELISA

  • 1:5,000-1:10,000

TARGET

UNIPROT #

PROTEIN NAME

Interleukin 31

SYNONYMS

IL 31 antibody; IL-31 antibody; IL31 antibody; IL31_HUMAN antibody; Interleukin 31 antibody; Interleukin-31 antibody

TISSUE SPECIFICITY

Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.

SUBCELLULAR LOCATION

Secreted

FUNCTION

Interleukin 31 (IL-31) is a secreted, T-cell-derived, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.