Mouse monoclonal primary
Interleukin 31 Mouse Monoclonal Antibody [B7-B0] (M1305-3)
Bioactive recombinant human IL-31 protein
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
IL 31 antibody; IL-31 antibody; IL31 antibody; IL31_HUMAN antibody; Interleukin 31 antibody; Interleukin-31 antibody
Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.
Interleukin 31 (IL-31) is a secreted, T-cell-derived, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.