Mouse monoclonal primary
Insulin Mouse Monoclonal Antibody [A6-6] (EM80714)
Rat pancreas tissue, human pancreas tissue, Insulin recombinant protein.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
IDDM antibody; IDDM1 antibody; IDDM2 antibody; ILPR antibody; ins antibody; INS_HUMAN antibody; Insulin A chain antibody; Insulin B chain antibody; IRDN antibody; MODY10 antibody; Preproinsulin antibody; Proinsulin antibody; Proinsulin precursor antibody
Belongs to the insulin family.
Insulin is a hormone with extensive effects on both metabolism and several other body systems. It causes most of the body's cells to take up glucose from the blood (including liver, muscle, and fat tissue cells), storing it as glycogen in the liver and muscle, and stops use of fat as an energy source. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to its secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide.
Xu, H., Du, X., Xu, J., ......
Xu, H., Du, X., Xu, J., Zhang, Y., Tian, Y., Liu, G., Wang, X., Ma, M., Du, W., Liu, Y., Dai, L., Huang, W., Tong, N., Wei, Y., & Fu, X. (2020). Pancreatic β cell microRNA-26a alleviates type 2 diabetes by improving peripheral insulin sensitivity and preserving β cell function. PLoS biology, 18(2), e3000603.