Rabbit polyclonal primary
IL1RL1 Rabbit Polyclonal Antibody (0902-2)
Synthetic peptide within n-terminal human il1rl1.
D3 cell, Zebrafish tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Immunogen affinity purified
DER-4 antibody; DER4 antibody; FIT 1 antibody; Growth stimulation expressed antibody; homolog of mouse growth stimulation-expressed antibody; Il1rl1 antibody; IL33R antibody; ILRL1_HUMAN antibody; Interleukin 1 receptor like 1 antibody; interleukin 1 receptor related protein antibody; Interleukin-1 receptor-like 1 antibody; Protein ST2 antibody; ST2 antibody; ST2L antibody; ST2V antibody; T1 antibody; T1 protein antibody
Belongs to the interleukin-1 receptor family.
Predominantly expressed in hematopoietic tissues, and in macrophage, erythroid, epithelial and fibroblast cell lines. Isoform A is expressed in brain astrocytes and microglia. Isoform B is expressed in brain endothelial cells.
Expressed first in the fetal liver and then in lung and hematopoietic tissues.
Cell membrane, Secreted.
The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle. Expressed on T-cells in fibrotic liver; at protein level. Overexpressed in fibrotic and cirrhotic liver.
Zhao, Guiyun et al.
Cell surface proteomics analysis indicates a neural lineage bias of rat bone marrow mesenchymal stromal cells. | BioMed Research International