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IL-19 Rabbit Polyclonal Antibody (ER1802-1)

Price: Regular price $315.00

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Catalog# ER1802-1

Rabbit Polyclonal to IL-19

Tested for

  • IF-Cell

  • IHC-P

Reacts with

  • Human

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

IL-19 Rabbit Polyclonal Antibody (ER1802-1)

Immunogen

Synthetic peptide within mouse il19 aa 127-176 / 176.

Host

Rabbit

Positive Control

Hela, HUVEC, SH-SY5Y, human tonsil tissue, human spleen tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3069107

APPLICATION DILUTION

  • IF-Cell

  • 1:50-1:200

  • IHC-P

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 20 kDa

Isotype

IgG

TARGET

UNIPROT #

Q9UHD0

PROTEIN NAME

IL-19

SYNONYMS

IL 10C antibody;IL 19 antibody;IL-19 antibody;Il19 antibody;IL19_HUMAN antibody;Interleukin 19 antibody;Interleukin-19 antibody;MDA1 antibody;Melanoma differentiation-associated protein-like protein antibody;NG.1 antibody;ZMDA1 antibody

SEQUENCE SIMILARITIES

Belongs to the IL-10 family.

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Interleukin 19 (IL-19) is an immunosuppressive protein that belongs to the IL-10 cytokine subfamily. IL-19 is associated with broad functions across inflammation, cell development, viral responses, and lipid metabolism. As an immunosuppressive cytokine, IL-19 promotes the Th2 (regulatory) T-cell response which supports an anti-inflammatory lymphocyte phenotype, dampens the Th1 T-cell response and inflammatory cytokine secretion (IFNγ), increases IL-10 (anti-inflammatory) expression in peripheral blood mononuclear cells (PBMC), and inhibits the production of immunoglobulin G (IgG) from B cells.

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