PRODUCT CODE: ER1802-1

IL19 Rabbit Polyclonal Antibody (ER1802-1)

Applications

  • ICC

  • IHC-P

REACTIVITY

  • Human

ICC staining IL19 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
  • ICC staining IL19 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
  • ICC staining IL19 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
  • ICC staining IL19 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IL19 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IL19 antibody. Counter stained with hematoxylin.
ICC staining IL19 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Applications

  • ICC

  • IHC-P

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

IL19 Rabbit Polyclonal Antibody (ER1802-1)

Immunogen

Synthetic peptide within mouse il19 aa 127-176 / 176.

Host

Rabbit

Positive Control

Hela, HUVEC, SH-SY5Y, human tonsil tissue, human spleen tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Peptide affinity purified

MOLECULAR WEIGHT

20 kDa

Isotype

IgG

APPLICATION DILUTION

  • ICC

  • 1:50-1:200

  • IHC-P

  • 1:50-1:100

TARGET

UNIPROT #

PROTEIN NAME

IL19

SYNONYMS

IL 10C antibody; IL 19 antibody; IL-19 antibody; Il19 antibody; IL19_HUMAN antibody; Interleukin 19 antibody; Interleukin-19 antibody; MDA1 antibody; Melanoma differentiation-associated protein-like protein antibody; NG.1 antibody; ZMDA1 antibody

SEQUENCE SIMILARITIES

Belongs to the IL-10 family.

SUBCELLULAR LOCATION

Secreted.

FUNCTION

IL-14 (high-molecular-weight B-cell growth factor or HMW-BCGF) is a 53kDa protein that plays a significant role in the rapid proliferation of aggressive B-cell type non-Hodgkin's lymphoma. IL-19 and IL-20 are IL-10-related cytokines. IL-19 is involved in melanoma differentiation, and IL-20 plays an essential role in epidermal function and psoriasis. Like other interleukin molecules, IL-21 is a small secreted molecule, and it has potent effects on lymphoid cells. IL-21 is most closely related to IL-2 and IL-15 and has a role in the proliferation and maturation of natural killer cell populations from bone marrow, in the proliferation of mature B-cell populations co-stimulated with anti-CD40, and in the proliferation of T cells co-stimulated with anti-CD3.