Positive control:
Lane 1: Jurkat cell lysate
Lane 2: Raji cell lysate
Lane 3: Daudi cell lysate
Applications
-
WB
-
IHC-P
REACTIVITY
-
Human
SPECIFICATIONS
Product Type
Mouse monoclonal primary
Product Name
IL-6 Mouse Monoclonal Antibody [7-A7] (EM30301)
Immunogen
Recombinant protein
Host
Mouse
Positive Control
Jurkat cell lysate, Raji cell lysate, Daudi cell lysate, human tonsil tissue.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
7-A7
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 ug/ul
PURIFICATION
Protein A purified.
MOLECULAR WEIGHT
24 kDa
Isotype
IgG1
APPLICATION DILUTION
-
WB
-
1:500
-
IHC-P
-
1:100-1:200
TARGET
UNIPROT #
PROTEIN NAME
IL-6
SYNONYMS
Interleukin BSF 2 antibody; B cell differentiation factor antibody; B cell stimulatory factor 2 antibody; B-cell stimulatory factor 2 antibody; BSF 2 antibody; BSF-2 antibody; BSF2 antibody; CDF antibody; CTL differentiation factor antibody; Hepatocyte stimulatory factor antibody; HGF antibody; HSF antibody; Hybridoma growth factor antibody; Hybridoma growth factor Interferon beta-2 antibody; IFN-beta-2 antibody; IFNB2 antibody; IL 6 antibody; IL-6 antibody; IL6 antibody; IL6_HUMAN antibody; Interferon beta 2 antibody; Interferon beta-2 antibody; Interleukin 6 antibody; Interleukin 6 (interferon beta 2) antibody; Interleukin BSF 2 antibody; Interleukin-6 antibody
SEQUENCE SIMILARITIES
Belongs to the IL-6 superfamily.
SUBCELLULAR LOCATION
Secreted
FUNCTION
Interleukin 6 (IL-6) is a potent pleiotropic cytokine that regulates cell growth and differentiation of various tissues, and is known particularly for its role in the immune response and acute phase reactions. IL-6 is a cytokine with a wide variety of biological functions and belongs to the?IL-6 superfamily. IL-6 is a potent inducer of the acute phase response and plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation.