IL-2 receptor alpha Rabbit Polyclonal Antibody (HA500076)

UNIPROT #

P01589

PROTEIN NAME

IL-2 receptor alpha

SYNONYMS

Interleukin 2 receptor alpha chain antibody;CD25 antibody;CD25 antigen antibody;IDDM10 antibody;IL 2 receptor alpha subunit antibody;IL-2 receptor subunit alpha antibody;IL-2-RA antibody;IL-2R subunit alpha antibody;IL2 RA antibody;IL2 Receptor alpha antibody;IL2-RA antibody;IL2R antibody;IL2R, alpha chain antibody;IL2RA antibody;IL2RA_HUMAN antibody;IMD41 antibody;Interleukin 2 receptor alpha antibody;Interleukin 2 receptor antibody;Interleukin-2 receptor subunit alpha antibody;p55 antibody;t-cell growth factor receptor antibody;TAC antibody;TAC antigen antibody;TCGFR antibody

SUBCELLULAR LOCATION

Membrane.

FUNCTION

Interleukin-2 receptor alpha chain (also called CD25) is a protein that in humans is encoded by the IL2RA gene.The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolysis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is currently unknown.