IGFBP1 Recombinant Rabbit Monoclonal Antibody - BSA and Azide free [PSH18-18] (HA751664)

UNIPROT #

P08833

PROTEIN NAME

IGFBP1

SYNONYMS

AFBP antibody;Alpha pregnancy associated endometrial globulin antibody;Amniotic fluid binding protein antibody;Binding protein 25 antibody;Binding protein 26 antibody;Binding protein 28 antibody;Growth hormone independent binding protein antibody;hIGFBP 1 antibody;hIGFBP1 antibody;IBP 1 antibody;IBP-1 antibody;IBP1 antibody;IBP1_HUMAN antibody;IGF binding protein 1 antibody;IGF BP25 antibody;IGF-binding protein 1 antibody;IGFBP 1 antibody;IGFBP-1 antibody;IGFBP1 antibody;Insulin like growth factor binding protein 1 antibody;Insulin-like growth factor-binding protein 1 antibody;Placental protein 12 antibody;PP 12 antibody;PP12 antibody

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Insulin-like growth factor-binding protein 1 (IBP-1) also known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene. This gene is a member of the Insulin-like growth factor-binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a type-I thyroglobulin domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.