PRODUCT CODE: M1301-2

ID2 Mouse Monoclonal Antibody [A4-D4] (M1301-2)

Applications

  • WB

  • ICC

  • IHC-P

REACTIVITY

  • Human

  • Mouse

Western blot analysis on recombinant  protein lysates using anti-ID2 Mouse mAb (Cat. # M1301-2).
  • Western blot analysis on recombinant  protein lysates using anti-ID2 Mouse mAb (Cat. # M1301-2).
  • Immunofluorescent staining of F9 cells using anti-ID2 Mouse mAb (Cat. # M1301-2).
  • Immunohistochemical analysis of paraffin- embedded human pancreatic cancer tissue using anti-ID2 Mouse mAb (Cat. # M1301-2).
Western blot analysis on recombinant protein lysates using anti-ID2 Mouse mAb (Cat. # M1301-2).

Applications

  • WB

  • ICC

  • IHC-P

REACTIVITY

  • Human

  • Mouse

SPECIFICATIONS

Product Type

Mouse monoclonal primary

Product Name

ID2 Mouse Monoclonal Antibody [A4-D4] (M1301-2)

Immunogen

Recombinant protein

Host

Mouse

Positive Control

F9

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

A4-D4

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

15 kDa

Isotype

IgG2b

APPLICATION DILUTION

  • WB

  • 1:1,000-1:10,000

  • ICC

  • 1:100

  • IHC-P

  • 1:100

TARGET

UNIPROT #

PROTEIN NAME

ID2

SYNONYMS

bHLHb26 antibody; Cell growth inhibiting gene 8 antibody; class B basic helix loop helix protein 26 antibody; Class B basic helix-loop-helix protein 26 antibody; DNA binding protein inhibitor ID 2 antibody; DNA binding protein inhibitor ID2 antibody; DNA-binding protein inhibitor ID-2 antibody; GIG 8 antibody; GIG8 antibody; Helix loop helix protein ID2 antibody; ID2 antibody; ID2_HUMAN antibody; ID2A antibody; ID2H antibody; Inhibitor of differentiation 2 antibody; Inhibitor of DNA binding 2 antibody; Inhibitor of DNA binding 2, dominant negative helix loop helix protein antibody; MGC26389 antibody

TISSUE SPECIFICITY

Highly expressed in early fetal tissues, including those of the central nervous system.

DEVELOPMENTAL STAGE

Found in most early fetal tissues but not in the corresponding mature tissues.

SUBCELLULAR LOCATION

Cytoplasm Nucleus

FUNCTION

DNA-binding protein inhibitor ID-2, is an inhibitor of differentiation protein, which, along with ID1, ID3, and ID4, plays a key role in the regulation of lineage commitment, cell fate decisions, and in the timing of differentiation during neurogenesis, lymphopoiesis, and neovascularization (angiogenesis). ID-2 may be an inhibitor of tissue-specific gene expression.