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Human Leptin Receptor, C-His Tag (ECD) Protein (HA211148)

Price: Regular price $379.00

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Catalog# HA211148

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  • Human

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Product Details

Product Type

Protein

Product Name

Human Leptin Receptor, C-His Tag (ECD) Protein (HA211148)

Predicted molecular mass

95.3 kD

Protein construction description

A DNA sequence encoding the human Leptin Receptor protein (P48357-1) (Phe 22-Asp 839) was expressed with a His tag at the C-terminus.

Accession

P48357-1

Protein construction

Leptin Receptor (22-839) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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