Lane 1: Human spleen tissue lysate
Lane 2: Human thymus tissue lysate
Lane 3: Human plasma tissue lysate
Recombinant Rabbit monoclonal primary
Human Kappa light chain Recombinant Rabbit Monoclonal Antibody [JE56-54] (HA720014)
Full length native human igg.
Human spleen tissue lysate, human thymus tissue lysate, human plasma tissue lysate, human tonsil tissue, human breast carcinoma tissue.
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
Human Kappa light chain
Immunoglobulin kappa variable 1D-16; Ig kappa chain V-I region HK146; Ig kappa chain V-I region HK189; Immunoglobulin kappa constant; Ig kappa chain C regionCurated; Ig kappa chain C region AG; Ig kappa chain C region CUM; Ig kappa chain C region EU; Ig kappa chain C region OU; Ig kappa chain C region ROY; Ig kappa chain C region TI
Cell membrane, Secreted.
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.