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Human EPCR/PROCR/CD201, C-His, Flag Tag (ECD) Protein (HA210662)

Price: Regular price $389.00

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Catalog# HA210662

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  • Human

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Product Details

Product Type

Protein

Product Name

Human EPCR/PROCR/CD201, C-His, Flag Tag (ECD) Protein (HA210662)

Predicted molecular mass

24.7 kD

Protein construction description

A DNA sequence encoding the human EPCR/PROCR/CD201 protein (Q9UNN8) (Ser 18-Ser 210) was expressed with both His, Flag tag at the C-terminus.

Accession

Q9UNN8

Protein construction

EPCR/PROCR/CD201 (18-210) | His | Flag

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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