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Human CD40/TNFRSF5, C-His Tag Protein (HA211232)

Price: Regular price $69.00

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Catalog# HA211232

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  • Human

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Product Details

Product Type

Protein

Product Name

Human CD40/TNFRSF5, C-His Tag Protein (HA211232)

Predicted molecular mass

21 kD

Protein construction description

A DNA sequence encoding the human CD40/TNFRSF5 (P25942-1) (Glu 21-Arg 193) was expressed with a His tag at the C-terminus.

Accession

P25942-1

Protein construction

CD40/TNFRSF5 (21-193) | His

Source

HEK293

Bio Activity

Testing in progress.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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