HTR3A Rabbit Polyclonal Antibody (HA500614)

UNIPROT #

P23979

PROTEIN NAME

HTR3A

SYNONYMS

5 HT 3 antibody;5 HT3 receptor antibody;5 HT3A antibody;5 HT3A receptor antibody;5 HT3RA antibody;5 hydroxytryptamine (serotonin) receptor 3A antibody;5-HT-3 antibody;5-HT3-A antibody;5-HT3A antibody;5-HT3R antibody;5-hydroxytryptamine receptor 3 antibody;5-hydroxytryptamine receptor 3A antibody;5HT receptor antibody;5HT3 serotonin receptor antibody;5HT3A_HUMAN antibody;5HT3R antibody;HTR3 antibody;Htr3a antibody;Serotonin receptor 3A antibody;Serotonin-gated ion channel receptor 3a antibody;Serotonin-gated ion channel receptor antibody

SUBCELLULAR LOCATION

Postsynaptic cell membrane, Cell membrane.

FUNCTION

5-hydroxytryptamine receptor 3A is a protein that in humans is encoded by the HTR3A gene. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. The A subunit is the only one that can be expressed alone and forms homomers with a very low single channel conductance of 0.6pS. When combined with the B subunit and expressed as a heteromer, the single channel conductance increases immensely. Alternatively spliced transcript variants encoding different isoforms have been identified.