HSPA2 Recombinant Rabbit Monoclonal Antibody [JJ08-77] (ET1701-15)

UNIPROT #

P54652

PROTEIN NAME

HSPA2

SYNONYMS

70kDa antibody;Hcp70.2 antibody;Heat shock 70 kDa protein 2 antibody;Heat shock protein 2 antibody;Heat shock protein 70.2 antibody;Heat shock related 70 kDa protein 2 antibody;Heat shock-related 70 kDa protein 2 antibody;Heat-shock protein, 70-KD, 2 antibody;Heat-shock protein, 70-KD, 3 antibody;HSP70 2 antibody;HSP70 3 antibody;Hsp70-2 antibody;HSP70-3 antibody;HSP70.2 antibody;HSP70A2 antibody;HSP72 antibody;HSP72_HUMAN antibody;HSPA2 antibody;Hspt70 antibody;Hst70 antibody;MGC58299 antibody;MGC7795 antibody;MGC93458 antibody;OTTHUMP00000180664 antibody;Testis-specific heat shock protein-related antibody

SEQUENCE SIMILARITIES

Belongs to the heat shock protein 70 family.

SUBCELLULAR LOCATION

Cytoplasm.

FUNCTION

HSPA2(heat shock 70kDa protein 2) also known as HEAT-SHOCK PROTEIN, 70-KD, 2, HSP70-2, HEAT-SHOCK PROTEIN, 70-KD, 3 or HSP70-3. Analysis of the sequence indicated that HSPA2 is the human homolog of the murine Hsp70-2 gene, with 91.7% identity in the nucleotide coding sequence and 98.2% in the corresponding amino acid sequence.HSPA2 has less amino acid homology to the other members of the human HSP70 gene family. HSPA2 is constitutively expressed in most tissues, with very high levels in testis and skeletal muscle. The HSPA2 gene is located on chromosome 14q22-q24. Immunohistochemical analysis detected weak expression of HSPA2 in spermatocytes and stronger expression in spermatids and in the tail of mature sperm. HSPA2 may be critical to sperm maturation through its role as a protein chaperone.