PRODUCT CODE: EM1701-78

HSPA1L Mouse Monoclonal Antibody [7D1] (EM1701-78)

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of HSPA1L on A549 (1) and mouse testis (2) lysate using anti-HSPA1L antibody at 1/10,000 dilution.
  • Western blot analysis of HSPA1L on A549 (1) and mouse testis (2) lysate using anti-HSPA1L antibody at 1/10,000 dilution.
  • Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-HSPA1L antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-HSPA1L antibody. Counter stained with hematoxylin.
Western blot analysis of HSPA1L on A549 (1) and mouse testis (2) lysate using anti-HSPA1L antibody at 1/10,000 dilution.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Mouse monoclonal primary

Product Name

HSPA1L Mouse Monoclonal Antibody [7D1] (EM1701-78)

Immunogen

Recombinant protein with human hspa1l aa 335-639 / 641.

Host

Mouse

Positive Control

A549, mouse testis tissue, rat testis tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

7D1

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2 ug/ul

PURIFICATION

Protein affinity purified.

MOLECULAR WEIGHT

70 kDa

Isotype

IgG1

APPLICATION DILUTION

  • WB

  • 1:10,000-1:50,000

  • IHC-P

  • 1:50-1:100

TARGET

UNIPROT #

PROTEIN NAME

HSPA1L

SYNONYMS

Heat shock 70 kDa protein 1 Hom antibody; Heat shock 70 kDa protein 1 like antibody; Heat shock 70 kDa protein 1-Hom antibody; Heat shock 70 kDa protein 1-like antibody; Heat shock 70 kDa protein 1L antibody; Heat shock 70kD protein like 1 antibody; HS71L_HUMAN antibody; HSP70 1L antibody; HSP70 HOM antibody; HSP70-Hom antibody; HSPA1L antibody; hum70t antibody; Spermatid specific heat shock protein 70 antibody

SEQUENCE SIMILARITIES

Belongs to the heat shock protein 70 family.

TISSUE SPECIFICITY

Expressed in spermatids.

SUBCELLULAR LOCATION

Cytosol. Secreted.

FUNCTION

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA1L (heat shock 70 kDa protein 1L), also known as HSP70T, is a 641 amino acid protein that belongs to the HSP 70 family and, like other HSP proteins, mediates protein folding within the cytosol, as well as within other organelles throughout the cell. HSP proteins, such as HSPA1L, together with chaperones, bind extended peptide segments with a net hydrophobic character exposed during protein translation, membrane translocation or after stress-induced damage. HSPA1L has been found be expressed in spermatids and is not induced by heat shock.