HOXA9 Rabbit Polyclonal Antibody (HA500135)

UNIPROT #

P31269

PROTEIN NAME

HOXA9

SYNONYMS

ABD-B antibody;Abd-B, drosophila, homolog of antibody;D6a9 antibody;Homeobox 1G antibody;Homeobox A9 antibody;Homeobox protein Hox-1.7 antibody;Homeobox protein Hox-1G antibody;Homeobox protein Hox-A9 antibody;Homeodomain protein HOXA9 antibody;Hox-1.7 antibody;Hox-1.7, mouse, homolog of antibody;HOX1 antibody;Hox1.7 antibody;Hox1G antibody;Hox1r5 antibody;Hoxa-9 antibody;Hoxa7 antibody;HOXA9 antibody;HOXA9/MSI2 fusion gene, included antibody;HOXA9/NUP98 fusion gene, included antibody;HXA9_HUMAN antibody;MGC1934 antibody

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.