Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
Western blot analysis of HFE on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (HA720039, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:200,000 dilution was used for 1 hour at room temperature.
Lane 1: Hela cell lysate
Lane 2: A431 cell lysate
dJ221C16.10.1 antibody;Hemochromatosis antibody;Hemochromatosis protein antibody;Hereditary hemochromatosis protein antibody;Hereditary hemochromatosis protein HLA H antibody;HFE 1 antibody;HFE antibody;HFE_HUMAN antibody;HFE1 antibody;HH antibody;High Fe antibody;HLA H antibody;HLA-H antibody;HLAH antibody;MGC:150812 antibody;MGC10379 antibody;MGC103790 antibody;MHC class I like protein HFE antibody;MVCD7 antibody;TFQTL2 antibody
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Just like the interactions between antigens and antibodies, the higher the affinity between you and us the better.