GSTK1 Recombinant Rabbit Monoclonal Antibody [JE47-38] (ET7109-58)

UNIPROT #

Q9Y2Q3

PROTEIN NAME

GSTK1

SYNONYMS

EC 2.5.1.18 antibody;Glutathione S Transferase kappa 1 antibody;Glutathione S transferase subunit 13 antibody;Glutathione S-transferase k1 antibody;Glutathione S-transferase kappa 1 antibody;Glutathione S-transferase subunit 13 antibody;Glutathione S-transferase subunit 13 homolog antibody;GST 13 13 antibody;GST 13-13 antibody;GST antibody;GST class kappa antibody;GST class-kappa antibody;GST13 antibody;GST13-13 antibody;GSTK1 1 antibody;Gstk1 antibody;GSTK1-1 antibody;GSTK1_HUMAN antibody;hGSTK1 antibody

SEQUENCE SIMILARITIES

Belongs to the GST superfamily. Kappa family.

TISSUE SPECIFICITY

Ubiquitous.

SUBCELLULAR LOCATION

Peroxisome.

FUNCTION

Glutathione S-transferase kappa 1 (GSTK1) is an enzyme that in humans is encoded by the GSTK1 gene which is located on chromosome seven. It belongs to the superfamily of enzymes known as glutathione S-transferase (GST), which are mainly known for cellular detoxification. The GSTK1 gene consists of eight exons and seven introns and although it is a member of the GST family, its structure has been found to be similar to bacterial HCCA (2-hydroxychromene-2-carboxylate) isomerases and bacterial disulphide-bond-forming DsbA oxidoreductase. Research has also suggested that several variations of the GSTK1 gene can be responsible for metabolic diseases and certain types of cancer. The amount of expression of adiponectin has been observed to be related to diseases such as insulin resistance, obesity, and type 2 diabetes. GSTK1 can also be a potential tool to help investigate cancer. Tyrosine phosphorylated proteins are responsible for many of the cell functions such as the cell’s growth, division, adhesion, and motility. These activities are also very related to cancer and thus studying this protein could allow access to information which could classify tumors for prognosis and prediction.