GST3 Rabbit Polyclonal Antibody (ER1802-63)
Catalog# ER1802-63
Rabbit Polyclonal to GST3
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WB
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IF-Cell
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IHC-P
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Human
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Mouse
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Rat
Positive control:
Lane 1: SiHa cell lysate
Lane 2: Hela cell lysate
Lane 3: A549 cell lysate
Lane 4: Mouse kidney tissue lysate
Lane 5: Rat liver tissue lysate
Specifications
Product Type
Rabbit polyclonal primary
Product Name
GST3 Rabbit Polyclonal Antibody (ER1802-63)
Immunogen
Recombinant protein within n-terminal human gst3.
Host
Rabbit
Positive Control
SiHa cell lysate, Hela cell lysate, A549 cell lysate, mouse kidney tissue lysate, rat liver tissue lysate, A549, HUVEC, LOVO, human liver cancer tissue, human placenta tissue.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:500-1:1,000
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IF-Cell
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1:500-1:1,000
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IHC-P
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1:50-1:200
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 23 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
GST3
SYNONYMS
Deafness antibody;Deafness X-linked 7 antibody;DFN7 antibody;FAEES3 antibody;Fatty Acid Ethyl Ester Synthase III antibody;Glutathione S Transferase 3 antibody;Glutathione S Transferase Pi antibody;Glutathione S-transferase P antibody;Glutathione S-transferase pi 1 antibody;GST class-pi antibody;GST3 antibody;GSTP antibody;Gstp1 antibody;GSTP1-1 antibody;GSTP1_HUMAN antibody;PI antibody;X linked 7 antibody
SEQUENCE SIMILARITIES
Belongs to the GST superfamily. Pi family.
SUBCELLULAR LOCATION
Cytoplasm. Mitochondrion, Nucleus.
FUNCTION
Glutathione S-transferases (GSTs) function in the metabolic detoxification of various environmental carcinogens and lipid hydroperoxides. In response to oxidative stress, upregulation of the GST family member GSTP1 occurs, consistent with this function. Furthermore, the GSTP1 gene is subject to CpG island hypermethylation, a state that correlates with human prostatic carcinogenesis. GSTP1 gene hypermethylation can be detected in urine, ejaculate and plasma from men with prostate cancer, potentially making GSTP1 a useful biomarker for prostate cancer screening.
CITATIONS
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Shu Guangjie,et al
Galangin alleviated Doxorubicin-induced cardiotoxicity by inhibiting ferroptosis through GSTP1/JNK pathway
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WB
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IF
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Rat
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Citation
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