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GST3 Rabbit Polyclonal Antibody (ER1802-63)

Price: Regular price $295.00

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Catalog# ER1802-63

Rabbit Polyclonal to GST3

Tested for

  • WB

  • ICC

  • IHC-P

React with

  • Human

  • Mouse

  • Rat

Specifications

Product Type

Rabbit polyclonal primary

Product Name

GST3 Rabbit Polyclonal Antibody (ER1802-63)

Immunogen

Recombinant protein within n-terminal human gst3.

Host

Rabbit

Positive Control

Siha, Hela, A549, mouse kidney tissue lysate, rat liver tissue lysate, HUVEC, LOVO, human liver cancer tissue, human placenta tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • ICC

  • 1:500-1:1,000

  • IHC-P

  • 1:50-1:200

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

23 kDa

Isotype

IgG

TARGET

UNIPROT #

P09211

PROTEIN NAME

GST3

SYNONYMS

Deafness antibody;Deafness X-linked 7 antibody;DFN7 antibody;FAEES3 antibody;Fatty Acid Ethyl Ester Synthase III antibody;Glutathione S Transferase 3 antibody;Glutathione S Transferase Pi antibody;Glutathione S-transferase P antibody;Glutathione S-transferase pi 1 antibody;GST class-pi antibody;GST3 antibody;GSTP antibody;Gstp1 antibody;GSTP1-1 antibody;GSTP1_HUMAN antibody;PI antibody;X linked 7 antibody

SEQUENCE SIMILARITIES

Belongs to the GST superfamily. Pi family.

SUBCELLULAR LOCATION

Nucleus. Cytoplasm. Mitochondrion.

FUNCTION

Glutathione S-transferases (GSTs) function in the metabolic detoxification of various environmental carcinogens and lipid hydroperoxides. In response to oxidative stress, upregulation of the GST family member GSTP1 occurs, consistent with this function. Furthermore, the GSTP1 gene is subject to CpG island hypermethylation, a state that correlates with human prostatic carcinogenesis. GSTP1 gene hypermethylation can be detected in urine, ejaculate and plasma from men with prostate cancer, potentially making GSTP1 a useful biomarker for prostate cancer screening.

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