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Gp83 Mouse Monoclonal Antibody [4D1] (EM1701-53)

Price: Regular price $350.00

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Catalog# EM1701-53

Mouse Monoclonal to Gp83

Tested for

  • WB

  • IF-Cell

  • IHC-P

Reacts with

  • Human

  • Mouse

  • Rat

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Specifications

Product Type

Mouse monoclonal primary

Product Name

Gp83 Mouse Monoclonal Antibody [4D1] (EM1701-53)

Immunogen

Recombinant protein with human adam17 aa 215-315 / 824.

Host

Mouse

Positive Control

SH-SY-5Y, PC-3M, rat epididymis tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

4D1

RRID

AB_3068777

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IF-Cell

  • 1:50-1:200

  • IHC-P

  • 1:50-1:200

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2ug/ul

Purification

Protein G affinity purified.

Molecular Weight

Predicted band size: 86 kDa

Isotype

IgG1

TARGET

UNIPROT #

Q9H2U9

PROTEIN NAME

Gp83

TISSUE SPECIFICITY

Not detected in healthy melanocytes. Expressed in melanoma cells.

SUBCELLULAR LOCATION

Membrane.

FUNCTION

This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein.

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