Rabbit polyclonal primary
GOT1 Rabbit Polyclonal Antibody (ER1802-48)
Recombinant protein within n-terminal human got1.
K562, human liver tissue, human colon tissue, human heart tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
CGI-141 antibody; GCT2 antibody; Germ cell tumor 2 antibody; Golgi transport 1 homolog B antibody; Golgi transport 1B antibody; GOLT1B antibody; GOT1 antibody; GOT1B_HUMAN antibody; hGOT1a antibody; Putative NF-kappa-B-activating protein 470 antibody; Vesicle transport protein GOT1B antibody; YMR292W antibody
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.