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GM-CSF-R-alpha (CD116) Rabbit Polyclonal Antibody (0804-8)

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Catalog# 0804-8

Rabbit Polyclonal to GM-CSF-R-alpha (CD116)

Tested for

  • WB

  • IF-Cell

  • IHC-P

  • FC

React with

  • Mouse

This product has been cited in peer reviewed publications, see list HERE

Specifications

Product Type

Rabbit polyclonal primary

Product Name

GM-CSF-R-alpha (CD116) Rabbit Polyclonal Antibody (0804-8)

Immunogen

Synthetic peptide within mouse gm-csf-r-alpha (cd116) aa 11-60 / 388.

Host

Rabbit

Positive Control

F9 cell lysates.

Conjugation

Unconjugated

Clonality

Polyclonal

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IF-Cell

  • 1:100-1:200

  • FC

  • 1:10-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 42 kDa

Isotype

IgG

TARGET

UNIPROT #

Q00941

PROTEIN NAME

GM-CSF-R-alpha (CD116)

SYNONYMS

CD_antigen=CD116 antibody;CD116 antibody;CD116 antigen antibody;CDw116 antibody;Colony stimulating factor 2 receptor alpha chain antibody;Colony stimulating factor 2 receptor alpha low affinity antibody;Colony stimulating factor 2 receptor alpha subunit antibody;CSF 2R antibody;CSF2R antibody;CSF2R_HUMAN antibody;CSF2RA antibody;CSF2RAX antibody;CSF2RAY antibody;CSF2RX antibody;CSF2RY antibody;GM CSF R alpha antibody;GM CSF receptor alpha subunit antibody;GM-CSF-R-alpha antibody;GMCSFR antibody;GMCSFR-alpha antibody;GMR-alpha antibody;Granulocyte macrophage colony stimulating factor receptor alpha chain antibody;Granulocyte-macrophage colony-stimulating factor receptor subunit alpha antibody;SMDP4 antibody

SEQUENCE SIMILARITIES

Belongs to the type I cytokine receptor family. Type 5 subfamily.

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

The granulocyte-macrophage colony-stimulating factor receptor also known as CD116 (Cluster of Differentiation 116), is a receptor for granulocyte-macrophage colony-stimulating factor, which stimulates the production of white blood cells. In contrast to M-CSF and G-CSF which are lineage specific, GM-CSF and its receptor play a role in earlier stages of development. The receptor is primarily located on neutrophils, eosinophils and monocytes/macrophages, it is also on CD34+ progenitor cells (myeloblasts) and precursors for erythroid and megakaryocytic lineages, but only in the beginning of their development. It is associated with Surfactant metabolism dysfunction type 4.

CITATIONS

  • Ming Zhang,Kangshou Yao

    Proteomic Analyses Reveal Common Promiscuous Patterns of Cell Surface Proteins on Human Embryonic Stem Cells and Sperms

  • Tan, Zhou et al.

    Production of rabbit monoclonal antibodies against mouse embryonic stem cells and identification of pluripotency-associated surface antigens. | Journal of Immunological Methods [2011]

  • Ming Zhang

    Global Expression of Cell Surface Proteins in Embryonic Stem Cells

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